









Climate change and maternal-child health Laboratory
Department of Developmental Biology and Genetics, Division of Biological Science
Indian Institute of Science, Bangalore, India



EMBO Global Investigator
INSA medal for young scientist
Infosys Young Investigator
Merck Young Scientist
DBT-Ramalingaswamy Fellow
Post-doc: Department of Human Genetics, University of Michigan, Ann Arbor, USA.
Phd: University of Calcutta, Kolkata, India
Current Members

Postdoctoral Fellow
Dr. Vani Venkatappa
Early mammalian development
Human embryo biomarkers and IVF outcome
Human IPSCs and ESCs, 3D-Organoids
I am from Bangalore, I obtained my PhD (Zoology) from Karnatak University, Post-doc from Dept. of Developmental Biology and Genetics (Formerly known as dept.of MRDG),Indian Institute of Science, India. Continued my post-doctoral journey at department of Dept. molecular and cellular biology, Baylor college of Medicine, Houston, USA. Currently, my research focuses on the early mammalian development, epigenetic regulation. Potentially exploring the human embryo-biomarkers on improving IVF outcome and investigating their translational potential using in vivo and stem-cell based in vitro 3D-organoid models. In my leisure time, I like to read and would check the updates across the world, on reproductive biomedicine research.

PhD Student
Runumi Baro
m6A RNA-methylation
Early development and cancer
X-chromosome inactivation
I am from Assam and did my Integrated Masters in Medical Biotechnology. My research is focussed on the role of m6A RNA modification in lineage specification during embryogenesis and dosage compensation in mammals. In my leisure time, I would just lie-down and check updates across the world.
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PhD student
Avinchal
Transgenerational Epigenetic Inheritance
Environmental epigenetics
I acquired a bachelor’s degree in biology from Himachal Pradesh University, Shimla and I am a postgraduate in Zoology honors from Panjab university, Chandigarh. I joined this lab in 2020 and currently I’m exploring the molecular basis of heat stress vulnerability to maternal-child health using mouse model system. In my leisure time I like to read poetry and history.

PhD Student
Swati Negi
m6A DNA-methylation
Early mammalian development
Epigenetic regulation in cancer
I have completed my M. Tech in marine biotechnology in 2021 and while studying marine biotech, I got interested in the impact of epigenome on organisms. Currently, I am looking into novel DNA modifications in several mouse embryonic lineages and planning to decipher the role of these modifications in a disease context as well. I love reading and writing. I also like to do swimming and art/craft in spare time.

PhD Student
Harshada S Jadhav
Epigenetic basis of PCOS pathogenesis
Naive and primed pluripotency
X-chromosome inactivation
Hello there! I'm from Mumbai. My PhD project entails deciphering the key molecular players in maintenance of X chromosome inactivation. In addition to this, I am working on understanding the epigenetic basis of PCOS in Indian women. I like to read, cycle, exercise and dance.

PhD Student (collaboration with Prof. Annapoorni Rangarajan)
Akshatha Nagarkatte
Epigenetic regulation in oral cancer stem cells
I am from Bangalore. I have completed my MSc in Human Disease Genetics from Centre for Human Genetics. My project aims to understand the epigenetic regulation of oral cancer stem cells. My hobbies include painting and singing.

Integrated MS-PhD Student
Amlan Jyoti Naskar
Autosomal random monoallelic expression (RME)
Transcriptional bursting
A Bengali by origin as also from heart, I am from Kolkata, West Bengal. There only I obtained my B.Sc. (Honours) degree in Life Sciences from the Presidency University and thereafter joined the Integrated PhD programme in Biological Science at IISc in 2020. Now in the lab, I am exploring the role of random monoallelic gene expression in early developmental cell fate specification and related epigenetic mechanisms. Outside the lab, you may find me exploring random street food, restaurants and breweries ; also sometimes I love to cook, bingewatch series and travel here and there.

PhD student (collaboration with Dr. Mohit Kumar Jolly)
Harshavardhan BV
Cancer Heterogeneity
I am Harshavardhan BV, a joint Ph.D student between Dr. Mohit Kumar Jolly and Dr. Srimonta Gayen under the IMI programme. I am from Chennai and I have completed my BS-MS at IISER Pune. I use mathematical and computational techniques to study heterogeneity in cancer. My hobbies include messing with computers and video games.

Project Assistant (Bioinformatician)
Hemant Chandru Naik
X-chromosome upregulation
Chromatin states

Integrated MS-PhD student
Sharmista Saha
Chromatin Structure and function
Epigenetic modifiers
I come from Kolkata (The City of Joy). I received my Bachelor's from Kalyani University in Molecular Biology and Biotechnology, my willingness to know more and curiosity for my subject drove me towards research. Got chance in IISc as an Int-PhD and an opportunity in SG Lab. Here, my major goal is to identify how epigenetic modifiers interact to nucleosome, deeper into structural aspects using Cryo-EM. I am also targeting to find out structural defects in mutational level for an autistic patient. Besides my research, in my leisure time I enjoy doing classical dance, mandala art, listening to folk music.P.S. I am also a very good baker!

Integrated MS-PhD student
Amritesh Sarkar
Epigenetic landscapes under environmental stressors
By origin, I belong to Kolkata. Biological complexity has always fascinated me, which drove me to pursue my PhD here at IISc Bangalore. Currently, I am invested in exploring the epigenetic dynamics of mammalian reproductive biology under environmental stressors with mouse as our model system. I prefer to spend my leisure time watching movies, social dramas and playing football.

Integrated MS-PhD Student
Aryan Kumar
X chromsome to autosome dosage compensation

Integrated MS-PhD student (collaboration with Prof. S. Swaminathan)
Satabdi Das
Kidney Epigenetics

PhD Student
Prathyusha S
To be entered
I hail from the land of coconuts and monsoon, Kerala. I did my Integrated MSc at the Central University of Tamil Nadu. In the lab, I explore how heat and humidity stress reshape the epigenetic patterns of embryonic stem cells in mice, connecting environment, biology, and climate change. Outside the lab, you’ll usually find me painting, drawing, exploring food places or buried in a book, keeping creativity and curiosity close at hand.

Integrated MS-PhD Student
Ankit Bhattacharyya
Effect of climate change in pregnancy complications
By origin I am from kolkata, I completed my Bachelor's in Zoology from Ramakrishna Mission Vivekananda Centenary College, Rahara. I have always been fasinated to study genetics and how the expression of the genes is regulated through various epigenetic modifications. Currently I am invested to study various pregnancy complicatios arising due to global warming. During my free time, I love to dance and do karate.

Integrated MS-PhD Student
Kripansha Pant
Impacts of climate change on pregnancy outcomes
I am originally from Uttarakhand and hold a Bachelor’s degree in Biomedical Sciences (Hons.) from Bhaskaracharya College of Applied Sciences, University of Delhi. My research interests stem from my curiosity about human variation and the question of what biological mechanisms make each individual unique. I am currently investigating the adverse effects of rising average global temperature on pregnancy outcomes. Alongside science, I enjoy reading and writing novels, travelling, exploring different cultures, stargazing and listening to music.

PhD Student (collaboration with Prof. Deepak Saini)
Yogesh
Epigenetic regulation of aging
I hold a Master’s degree in Applied Nutrition from the ICMR–National Institute of Nutrition, Hyderabad. During my master’s thesis, I developed an interest in aging and later joined this lab to explore the link between the epigenome and metabolome in aging among the Indian population. Outside the lab, spare hours go to lifting, spare days to painting, and spare weeks to animating.

PhD Student (collaboration with Prof. Annapoorni Rangarajan)
Saleheen Jahan
Epigenetics and cancer stem cells
I have done my master's degree in biotechnology from Jamia Millia Islamia, New Delhi. During my master I have done my dissertation at topic " Purification of Nucleobindin 1 protein" from CSIR-IGIB, New Delhi. Later joined this lab exploring the impact of epigenetic changes on stem cell biology, including effects of heat stress on mammary gland development, differentiation, lactation etc, using mice models. Outside the lab I love to do calligraphy, Sketching, read novels and spending time with my friends and family for healthy mental peace.

Junior Research Fellow (collaboration with Prof. Deepak Saini)
Meet Makwana
Epigenetics and Aging
I completed my B.Sc. (Honours) in Microbiology from the University of Delhi and went on to pursue my Master’s in Biotechnology from The Maharaja Sayajirao University of Baroda, where I developed a strong interest in aging research. Currently, my project focuses on understanding the implications of epigenetics in aging, with a particular emphasis on biomarker discovery for the Indian population. My broader interests include philosophy, martial arts, and reading novels.
Alumni

Integrated MS-PhD Student
Dr. Maniteja Arava
Past Members
Akash Kalita, Current Position: PhD at IMPRS-MOB, Germany Priasha Karmakar, Current Position: PhD at Indian Institute of Science, Bangalore Parichitran A, Current Position: Universita’ Federico II di Napoli Girija Shankar Bariha, Current Position: Post-Research Fellow at CIIRC, Bengaluru Ankit Jana, Current Position: PhD at National University of Singapore, Singapore Karunyaa M, currently working at Jubilant Biosys Limited Amitesh Panda, Current Position: PhD at KU Leuven, Belgium Susmita Mandal, Current Position: PhD at Charité Universitätsmedizin, Berlin, Germany Annesha Ghosh, Current Position: PhD at IISER-Mohali, India Aditi Sundaresh, Current Position: PhD at Institute for Molecular Medicine Finland (FIMM) Bagyashree Thiruneelakandan Deepshikha Chandel Harman Kaur Praharshit Sharma Abheek Sengupta Pavithra RV Roni Saiba Veena Pooja Roy Neha Singh Rayees Michelle de Rosario Anu Arun Shreya Ghosh Keerthi Shetty Dr. Sowjanya Bammidi Raghunandan D R Shibam Chakraborty Karishma Aniruddha Nayak




