Chromatin, RNA & Genome Laboratory
Department of Developmental Biology and Genetics, Division of Biological Science
Indian Institute of Science, Bangalore, India
Post-doc: Department of Human Genetics, University of Michigan, Ann Arbor, USA.
Phd: University of Calcutta, Kolkata, India
EMBO Global Investigator
INSA medal for young scientist
Infosys Young Investigator
Merck Young Scientist
DBT-Ramalingaswamy Fellow
Current President of GENESIS, DBG
Current Members
Postdoctoral Fellow
Dr. Lakshmi Soujanya
CTCF
X-chromosome inactivation
Sexual dimorphism
DST-Women Scientist
Integrated MS-PhD Student
Maniteja Arava
Maintenance of X-chromosome inactivation
I am from Andhra Pradesh. I joined IISc in 2016 as an Int PhD student. I have continued my research journey with Dr. Gayen since 2017. I am blessed to investigate epigenetic cellular memory using X-chromosome inactivation as a model system. We reported the significance of Xist, DNA methylation and various chromatin states in the maintenance of inactive X chromosome for the lifetime. In leisure, I spent time talking to family members, tasting a diverse variety of cuisines, and movies, playing with pets and gardening.
PhD Student
Runumi Baro
m6A RNA-methylation
Early development and cancer
X-chromosome inactivation
I am from Assam and did my Integrated Masters in Medical Biotechnology. My research is focussed on the role of m6A RNA modification in lineage specification during embryogenesis and dosage compensation in mammals. In my leisure time, I would just lie-down and check updates across the world.
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PhD student
Avinchal
Transgenerational Epigenetic Inheritance
Environmental epigenetics
I acquired a bachelor’s degree in biology from Himachal Pradesh University, Shimla and I am a postgraduate in Zoology honors from Panjab university, Chandigarh. I joined this lab in 2020 and currently I’m exploring the molecular basis of heat stress vulnerability to maternal-child health using mouse model system. In my leisure time I like to read poetry and history.
PhD Student
Swati Negi
m6A DNA-methylation
Early mammalian development
Epigenetic regulation in cancer
I have completed my M. Tech in marine biotechnology in 2021 and while studying marine biotech, I got interested in the impact of epigenome on organisms. Currently, I am looking into novel DNA modifications in several mouse embryonic lineages and planning to decipher the role of these modifications in a disease context as well. I love reading and writing. I also like to do swimming and art/craft in spare time.
Integrated MS-PhD Student
Amlan Jyoti Naskar
Autosomal random monoallelic expression (RME)
Transcriptional bursting
A Bengali by origin as also from heart, I am from Kolkata, West Bengal. There only I obtained my B.Sc. (Honours) degree in Life Sciences from the Presidency University and thereafter joined the Integrated PhD programme in Biological Science at IISc in 2020. Now in the lab, I am exploring the role of random monoallelic gene expression in early developmental cell fate specification and related epigenetic mechanisms. Outside the lab, you may find me exploring random street food, restaurants and breweries ; also sometimes I love to cook, bingewatch series and travel here and there.
Integrated MS-PhD student
Sharmista Saha
Chromatin Structure and function
Epigenetic modifiers
I come from Kolkata (The City of Joy). I received my Bachelor's from Kalyani University in Molecular Biology and Biotechnology, my willingness to know more and curiosity for my subject drove me towards research. Got chance in IISc as an Int-PhD and an opportunity in SG Lab. Here, my major goal is to identify how epigenetic modifiers interact to nucleosome, deeper into structural aspects using Cryo-EM. I am also targeting to find out structural defects in mutational level for an autistic patient. Besides my research, in my leisure time I enjoy doing classical dance, mandala art, listening to folk music.P.S. I am also a very good baker!
PhD Student
Harshada S Jadhav
Epigenetic basis of PCOS pathogenesis
Naive and primed pluripotency
X-chromosome inactivation
Hello there! I'm from Mumbai. My PhD project entails deciphering the key molecular players in maintenance of X chromosome inactivation. In addition to this, I am working on understanding the epigenetic basis of PCOS in Indian women. I like to read, cycle, exercise and dance.
PhD student (collaboration with Dr. Mohit Kumar Jolly)
Harshavardhan BV
Cancer Heterogeneity
I am Harshavardhan BV, a joint Ph.D student between Dr. Mohit Kumar Jolly and Dr. Srimonta Gayen under the IMI programme. I am from Chennai and I have completed my BS-MS at IISER Pune. I use mathematical and computational techniques to study heterogeneity in cancer. My hobbies include messing with computers and video games.
Integrated MS-PhD student
Amritesh Sarkar
Epigenetic landscapes under environmental stressors
By origin, I belong to Kolkata. Biological complexity has always fascinated me, which drove me to pursue my PhD here at IISc Bangalore. Currently, I am invested in exploring the epigenetic dynamics of mammalian reproductive biology under environmental stressors with mouse as our model system. I prefer to spend my leisure time watching movies, social dramas and playing football.
PhD Student (collaboration with Prof. Annapoorni Rangarajan)
Akshatha Nagarkatte
Epigenetic regulation in oral cancer stem cells
I am from Bangalore. I have completed my MSc in Human Disease Genetics from Centre for Human Genetics. My project aims to understand the epigenetic regulation of oral cancer stem cells. My hobbies include painting and singing.
UG student
Akash Kalita
Mammalian dosage compensation
X-chromosome inactivation
I'm a 5th year UG student at IISc and joined the lab in 2022 following my interest in dosage compensation(XCI) for an in-semester project, and continued working here for my BS and MS theses. My research interest is in development and regeneration via stem cell model(s). Outside of lab, you can find me communicating science, reading novels, trekking or playing.
MSc student
Priasha Karmakar
Structural characterization of mammalian epigenetic modifiers
A 2022 graduate from Presidency University, Kolkata, Currently interested in studying protein structure and function. Outside the lab, finds solace in the world of short stories.
Project Assistant (Bioinformatician)
Hemant Chandru Naik
X-chromosome upregulation
Chromatin states
Project Assistant (Bioinformatician)
Parichitran Ayyamperumal
Transcriptional burst kinetics
Cell fate specification
Hey, I am Parichitran Ayyamperumal hailing from Theni,TN .Currently I am working to find how cells decides to differentiate either in developmental or in disease context using the lens of transcriptional bursting,Random monoallelic expression,X-chromosome inactivation.
Masters Dissertation student
Raghunandan D R
X-chromosome inactivation
I hail from Bangalore. I am a final year BS-MS student from IISER Pune and currently working on my master's dissertation project in the lab on the role of CIZ1 in imprinted X inactivation. I am interested in epigenetics in development and disease and also immunology in cancer and autoimmune diseases. Besides, I like trekking, playing badminton and drumming.
